Interclass GPCR heteromerization affects localization and trafficking

Membrane trafficking processes regulate G protein-coupled receptor (GPCR) activity. Although class A GPCRs are capable of activating G proteins in a monomeric form, they can also potentially assemble into functional GPCR heteromers. Here, we showed that the class A serotonin 5-HT(2A) receptors (5-HT...

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Udgivet i:Sci Signal
Main Authors: Toneatti, Rudy, Shin, Jong M., Shah, Urjita H., Mayer, Carl R., Saunders, Justin M., Fribourg, Miguel, Arsenovic, Paul T., Janssen, William G., Sealfon, Stuart C., López-Giménez, Juan F., Benson, Deanna L., Conway, Daniel E., González-Maeso, Javier
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717648/
https://ncbi.nlm.nih.gov/pubmed/33082287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaw3122
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