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Small molecule recognition of disease-relevant RNA structures

Targeting RNAs with small molecules represents a new frontier in drug discovery and development. The rich structural diversity of folded RNAs offers a nearly unlimited reservoir of targets for small molecules to bind, similar to small molecule occupancy of protein binding pockets, thus creating the...

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Dades bibliogràfiques
Publicat a:Chem Soc Rev
Autors principals: Meyer, Samantha M., Williams, Christopher C., Akahori, Yoshihiro, Tanaka, Toru, Aikawa, Haruo, Tong, Yuquan, Childs-Disney, Jessica L., Disney, Matthew D.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717589/
https://ncbi.nlm.nih.gov/pubmed/32975549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cs00560f
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