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SkewIT: The Skew Index Test for large-scale GC Skew analysis of bacterial genomes

GC skew is a phenomenon observed in many bacterial genomes, wherein the two replication strands of the same chromosome contain different proportions of guanine and cytosine nucleotides. Here we demonstrate that this phenomenon, which was first discovered in the mid-1990s, can be used today as an ana...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Lu, Jennifer, Salzberg, Steven L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717575/
https://ncbi.nlm.nih.gov/pubmed/33275607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008439
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