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Quantitative analysis of replication-related mutation and selection pressures in bacterial chromosomes and plasmids using generalised GC skew index

BACKGROUND: Due to their bi-directional replication machinery starting from a single finite origin, bacterial genomes show characteristic nucleotide compositional bias between the two replichores, which can be visualised through GC skew or (C-G)/(C+G). Although this polarisation is used for computat...

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Detalhes bibliográficos
Main Authors: Arakawa, Kazuharu, Suzuki, Haruo, Tomita, Masaru
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804667/
https://ncbi.nlm.nih.gov/pubmed/20042086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-640
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