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Metformin alleviates β-glycerophosphate-induced calcification of vascular smooth muscle cells via AMPK/mTOR-activated autophagy

The aim of the present study was to investigate the effect of metformin on β-glycerophosphate-induced calcification of vascular smooth muscle cells (VSMCs) and the possible mechanisms underlying this. Using an established VSMC calcification model, VSMCs were first treated with β-glycerophosphate, be...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Qiu, Xiaobo, Xu, Qing, Xu, Tianhua, Wan, Pengzhi, Sheng, Zitong, Han, Yiran, Yao, Li
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716633/
https://ncbi.nlm.nih.gov/pubmed/33365058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9490
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