Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway

As a newly approved oral hypoglycaemic agent, the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin, which is derived from the natural product phlorizin can effectively reduce blood glucose. Recent clinical studies have found that dapagliflozin alleviates non-alcoholic fatty liver disea...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Liuran, Li, Qinghua, Huang, Wenbin, Han, Yibing, Tan, Huiting, An, Min, Xiang, Qianru, Zhou, Rui, Yang, Li, Cheng, Yanzhen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176308/
https://ncbi.nlm.nih.gov/pubmed/34093169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.589273
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