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RNA Drug discovery: Conformational restriction enhances specific modulation of the T-Box riboswitch function
Antibacterial drug resistance is a global health concern that requires multiple solution approaches including development of new antibacterial compounds acting at novel targets. Targeting regulatory RNA is an emerging area of drug discovery. The T-box riboswitch is a regulatory RNA mechanism that co...
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| Udgivet i: | Bioorg Med Chem |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7716477/ https://ncbi.nlm.nih.gov/pubmed/33069065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115696 |
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