The biogenesis and roles of extrachromosomal oncogene involved in carcinogenesis and evolution

More and more extrachromosomal DNA (ecDNA) was found in human tumor cells in recent years, which has a high copy number in tumors and changes the expression of oncogenes, thus different from normal chromosomal DNA. These circular structures were identified to originate from chromosomes, and play cri...

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Wei, Jianxia, Wu, Chunchun, Meng, Hanbing, Li, Mengna, Niu, Weihong, Zhan, Yuting, Jin, Long, Duan, Yumei, Zeng, Zhaoyang, Xiong, Wei, Li, Guiyuan, Zhou, Ming
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2020
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Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716155/
https://ncbi.nlm.nih.gov/pubmed/33294253
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