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Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunities
c-Met is a receptor tyrosine kinase belonging to the MET (MNNG HOS transforming gene) family, and is expressed on the surfaces of various cells. Hepatocyte growth factor (HGF) is the ligand for this receptor. The binding of HGF to c-Met initiates a series of intracellular signals that mediate embryo...
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| Publicado no: | Mol Cancer |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817860/ https://ncbi.nlm.nih.gov/pubmed/29455668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0796-y |
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