BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer

BRD7 functions as a crucial tumor suppressor in numerous malignancies. However, the effects of BRD7 on colorectal cancer (CRC) progression are still unknown. Here, based on the BRD7 knockout (BRD7(–/–)) and BRD7(flox/flox) (BRD7(+/+)) mouse models constructed in our previous work, we established an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Dev Biol
Prif Awduron: Zhao, Ran, Liu, Yukun, Wu, Chunchun, Li, Mengna, Wei, Yanmei, Niu, Weihong, Yang, Jing, Fan, Songqing, Xie, Yong, Li, Hui, Wang, Wei, Zeng, Zhaoyang, Xiong, Wei, Li, Xiaoling, Li, Guiyuan, Zhou, Ming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Cell and Developmental Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181413/
https://ncbi.nlm.nih.gov/pubmed/34109174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.659392
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