DIPG-39. NOVEL PROTEOMIC ANALYSIS REVEALS EPIGENETIC THERAPEUTIC TARGETS IN PEDIATRIC GLIOMA

INTRODUCTION: Diffuse midline glioma is a highly morbid pediatric cancer. Up to 80% harbor Histone H3K27M mutation, which alters Histone H3 post-translational modifications (PTMs) and genomic enrichment patterns, affecting chromatin structure and transcription. We previously identified tumorigenic p...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Li, Daphne, Huang, Tina, Camarillo, Jeannie, Piunti, Andrea, Qi, Jin, An, Shejuan, Nazarian, Javad, Thomas, Paul, Saratsis, Amanda
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Diffuse Midline Glioma/DIPG
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715980/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.086
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