DIPG-57. TRANSCRIPTOMIC AND PROTEOMIC ANALYSES OF DIPG RESPONSE TO ONC201

Diffuse Intrinsic Pontine Glioma (DIPG) is an incurable pediatric brain tumor. Current standard of care has shown no improvements in survival. Here, we report our study of ONC201, a first-in-class small molecule developed by Oncoceutics, Inc., against a panel of DIPG cells in vitro and in mouse orth...

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Vydáno v:Neuro Oncol
Hlavní autoři: Sridharan, Sreepradha, Harmanci, Arif, Sharma, Ajay, Lai, Yanlai, Kennis, Bridget, Dobson, Tara, Swaminathan, Jyothishmathi, Haltom, Amanda, Khatua, Soumen, Tarapore, Rohinton, Allen, Joshua, Cheng, Donghang, Zaky, Wafik, Gopalakrishnan, Vidya
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Diffuse Midline Glioma/DIPG
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715398/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.102
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