DIPG-57. TRANSCRIPTOMIC AND PROTEOMIC ANALYSES OF DIPG RESPONSE TO ONC201

Diffuse Intrinsic Pontine Glioma (DIPG) is an incurable pediatric brain tumor. Current standard of care has shown no improvements in survival. Here, we report our study of ONC201, a first-in-class small molecule developed by Oncoceutics, Inc., against a panel of DIPG cells in vitro and in mouse orth...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Sridharan, Sreepradha, Harmanci, Arif, Sharma, Ajay, Lai, Yanlai, Kennis, Bridget, Dobson, Tara, Swaminathan, Jyothishmathi, Haltom, Amanda, Khatua, Soumen, Tarapore, Rohinton, Allen, Joshua, Cheng, Donghang, Zaky, Wafik, Gopalakrishnan, Vidya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Diffuse Midline Glioma/DIPG
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715398/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.102
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