DIPG-57. TRANSCRIPTOMIC AND PROTEOMIC ANALYSES OF DIPG RESPONSE TO ONC201

Diffuse Intrinsic Pontine Glioma (DIPG) is an incurable pediatric brain tumor. Current standard of care has shown no improvements in survival. Here, we report our study of ONC201, a first-in-class small molecule developed by Oncoceutics, Inc., against a panel of DIPG cells in vitro and in mouse orth...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Sridharan, Sreepradha, Harmanci, Arif, Sharma, Ajay, Lai, Yanlai, Kennis, Bridget, Dobson, Tara, Swaminathan, Jyothishmathi, Haltom, Amanda, Khatua, Soumen, Tarapore, Rohinton, Allen, Joshua, Cheng, Donghang, Zaky, Wafik, Gopalakrishnan, Vidya
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Diffuse Midline Glioma/DIPG
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715398/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.102
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