MBRS-20. CSF-DERIVED CIRCULATING TUMOR DNA AS A BIOMARKER FOR DISEASE PROGRESSION AND TUMOR EVOLUTION IN MEDULLOBLASTOMA

BACKGROUND: Cell-free DNA (cfDNA) profiling has been shown to carry utility as a clinically relevant biomarker in a variety of cancers, but studies in pediatric brain tumors, including medulloblastoma, are scarce. We hereby evaluated the actionability of profiling cfDNA from cerebrospinal fluid (CSF...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Liu, Anthony Pak-Yin, Kumar, Rahul, Kyle, Smith, Paul, Leena, Chintagumpala, Murali, Bouffet, Eric, Fisher, Michael J, Hassall, Tim, Gururangan, Sri, Hansford, Jordan, Cohn, Richard, Ellison, David W, Gilbertson, Richard J, Gajjar, Amar, Robinson, Giles W, Northcott, Paul A
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Medulloblastoma (Research)
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715976/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.536
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