MODL-28. IMMUNE PRIMING WITH INTERFERON-Γ COMBINED WITH EPIGENETIC MODULATION IN PEDIATRIC BRAIN TUMORS

Systemic interferon-γ (IFNγ) has been shown to induce major histocompatibility complex class I (MHC-I) and T cell infiltration in solid tumors in adult patients, demonstrating a potential strategy to abrogate tumor-intrinsic mechanisms of immune escape. Pediatric brain tumors (PBT) may be particular...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Crotty, Erin, Morris, Shelli, Brasel, Ken, Girard, Emily, Noll, Alyssa, Mhyre, Andrew, Olson, James
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Preclinical Models/Experimental Therapy/Drug Discovery
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715937/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.601
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