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MODL-02. TARGETING REPLICATION STRESS IN PEDIATRIC BRAIN TUMORS
Pediatric brain tumors harboring amplifications or high overexpression of MYC-/MYCN are often associated with poor outcome. High MYC(N) expression in these tumors leads to increased transcription, which can be in conflict with DNA replication and subsequently can cause replication stress, R-loops an...
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| Gepubliceerd in: | Neuro Oncol |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7715544/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.579 |
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