DIPG-18. IDENTIFICATION OF TARGETABLE PATHWAY DEPENDENCIES IN DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse Intrinsic Pontine Glioma (DIPG) is a highly aggressive paediatric brainstem tumour with a dismal prognosis. Recurrent heterozygous mutations (p.K27M) in Histone H3 variant genes have been identified in the majority of DIPG cases. While the exact mechanism of H3K27M’s function is poorly under...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Parackal, Sarah, Chong, Wai Chin, Bradshaw, Gabrielle, Sun, Claire, Daniel, Paul, Roussel, Enola, Jayasekara, Samantha, Crombie, Duncan, Firestein, Ron, Cain, Jason
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Diffuse Midline Glioma/DIPG
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715817/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.068
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg