IMMU-14. IMMUNE CHECKPOINT INHIBITOR THERAPY FOR TREATMENT OF SYNCHRONOUS CANCERS IN PAEDIATRIC PATIENTS WITH CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY

Constitutional mismatch repair deficiency (CMMRD) is an autosomal recessive condition in which affected patients carry biallelic germline mutations in the MMR genes. This highly penetrant syndrome results in nearly universal development of malignant neoplasms at a young age, most commonly pediatric...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Henderson, Jacob, Morgenstern, Daniel, Edwards, Melissa, Sudhaman, Sumedha, Kram, David, Osborn, Michael, Cho, Yoon-Jae, Tabori, Uri
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Immunotherapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715753/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.370
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