IMMU-23. TARGETING THE CD200 CHECKPOINT TO ENHANCE IMMUNOTHERAPY FOR CNS TUMORS

Numerous clinical trials targeting immune checkpoints have failed to enhance survival in patients with CNS tumors. We are targeting a unique checkpoint, CD200, which controls the immune system through paired inhibitory and activation receptors. The CD200 checkpoint interferes with tumor-immune inter...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Moertel, Christopher, Pluhar, G Elizabeth, Ampudia-Mesias, Elisabet, Xiong, Zhengming, Pennell, Christopher A, Rathe, Susan K, Largaespada, David A, Olin, Michael R
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Immunology/Immunotherapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477440/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.142
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