CADD-14. TARGETING THE CD200 CHECKPOINT FOR THE FIGHT AGAINST CENTRAL NERVOUS SYSTEM TUMORS

Numerous ongoing clinical trials targeting immune checkpoints have failed to enhance survival in patients with CNS tumors. We are targeting a unique checkpoint, CD200, which controls the immune system through paired inhibitory and activation receptors. The CD200 checkpoint interferes with tumor-immu...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Olin, Michael, Ampudia-Mesias, Elisabet, Pennell, Christopher A, Xiong, Zhengming, Rathe, Susan K, Largaespada, David A, Moertel, Christopher L, Pluhar, G Elizabeth
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216804/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1159
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