CADD-14. TARGETING THE CD200 CHECKPOINT FOR THE FIGHT AGAINST CENTRAL NERVOUS SYSTEM TUMORS

Numerous ongoing clinical trials targeting immune checkpoints have failed to enhance survival in patients with CNS tumors. We are targeting a unique checkpoint, CD200, which controls the immune system through paired inhibitory and activation receptors. The CD200 checkpoint interferes with tumor-immu...

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Vydáno v:Neuro Oncol
Hlavní autoři: Olin, Michael, Ampudia-Mesias, Elisabet, Pennell, Christopher A, Xiong, Zhengming, Rathe, Susan K, Largaespada, David A, Moertel, Christopher L, Pluhar, G Elizabeth
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216804/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1159
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