EPCT-13. CMV PP65 RNA-PULSED DENDRITIC CELL VACCINES FOR PEDIATRIC GLIOBLASTOMA AND MEDULLOBLASTOMA: PHASE I TRIAL RESULTS

BACKGROUND: Recurrent medulloblastoma and malignant glioma are lethal tumors that are virtually incurable. The cytomegalovirus (CMV) antigen pp65 is ubiquitously expressed on medulloblastoma and malignant glioma but not on healthy brain. We evaluated autologous CMV pp65 RNA-pulsed dendritic cell (DC...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Landi, Daniel, Archer, Gary, Driscoll, Timothy, Lipp, Eric, Archambault, Bridget, Thompson, Eric, Flahiff, Charlene, Jaggers, Denise, Hahn, Kathleen, Healy, Patrick, Ramirez, Luis, Herndon, James, Schroeder, Kristin, Sampson, John, Ashley, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Early Phase Clinical Trials
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715746/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.136
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