EPCT-13. CMV PP65 RNA-PULSED DENDRITIC CELL VACCINES FOR PEDIATRIC GLIOBLASTOMA AND MEDULLOBLASTOMA: PHASE I TRIAL RESULTS

BACKGROUND: Recurrent medulloblastoma and malignant glioma are lethal tumors that are virtually incurable. The cytomegalovirus (CMV) antigen pp65 is ubiquitously expressed on medulloblastoma and malignant glioma but not on healthy brain. We evaluated autologous CMV pp65 RNA-pulsed dendritic cell (DC...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Landi, Daniel, Archer, Gary, Driscoll, Timothy, Lipp, Eric, Archambault, Bridget, Thompson, Eric, Flahiff, Charlene, Jaggers, Denise, Hahn, Kathleen, Healy, Patrick, Ramirez, Luis, Herndon, James, Schroeder, Kristin, Sampson, John, Ashley, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Early Phase Clinical Trials
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715746/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.136
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