DIPG-12. TARGETING EPIGENETIC MODIFIERS TO INDUCE IMMUNE SIGNALING IN DIPG

DIPG is a universally fatal pediatric brainstem tumor with no effective therapy. Recent work has shown that over 80% of DIPG cases harbor the H3K27M mutation leading to global loss of the repressive H3K27 trimethylation mark, global DNA hypomethylation, and a distinct gene expression signature. We s...

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Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Tetens, Ashley, Martin, Allison, Arnold, Antje, Novak, Orlandi, Eberhart, Charles, Feinberg, Andrew, Raabe, Eric, Koldobskiy, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2020
Gaiak:
Diffuse Midline Glioma/DIPG
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715404/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.062
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