LGG-51. BRAF ALTERATIONS IN PEDIATRIC LOW-GRADE GLIOMAS: RESULTS FROM A BRAZILIAN COHORT

BACKGROUND: Pediatric low grade gliomas (PLGG) are the most common central nervous system neoplasms in children. These are driven almost exclusively by alterations in the RAS/MAPK pathway. Specifically, alterations in the BRAF gene have emerged as an important target for therapy. This study aimed to...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Restine, Felipe, Sakamoto, Luis Henrique, Real, Juliana Monte, Pereira, Gregorio, Fernandes, Jennifer Marx, Aguiar, Simone dos Santos, Epelman, Sidnei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Low Grade Glioma
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715402/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.429
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