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LGG-09. PD-L1 EXPRESSION IN PEDIATRIC LOW GRADE GLIOMAS, AN OPPORTUNITY FOR INTERVENTION INDEPENDENT OF BRAF MUTATIONAL STATUS

10–15% of all pediatric gliomas harbor a point mutation in the BRAF gene, BRAF(V600E), and it is especially common in certain low grade subtypes. Targeting this mutation with BRAF inhibitors has generated impressive responses in pediatric brain tumor patients with multiple clinical trials ongoing. I...

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Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Martin, Allison, Bell, Robert, Yuan, Ming, Harris, Lauren, Arnold, Antje, Poore, Brad, Asnaghi, Laura, Raabe, Eric, Eberhart, Charles
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477325/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.152
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