MBRS-46. CHARTING NEOPLASTIC AND IMMUNE CELL HETEROGENEITY IN HUMAN AND GEM MODELS OF MEDULLOBLASTOMA USING scRNAseq

We explored cellular heterogeneity in medulloblastoma using single-cell RNA sequencing (scRNAseq), immunohistochemistry and deconvolution of bulk transcriptomic data. Over 45,000 cells from 31 patients from all main subgroups of medulloblastoma (2 WNT, 10 SHH, 9 GP3, 11 GP4 and 1 GP3/4) were cluster...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Donson, Andrew, Riemondy, Kent, Venkataraman, Sujatha, Gilani, Ahmed, Sanford, Bridget, Griesinger, Andrea, Amani, Vladimir, Hankinson, Todd, Handler, Michael, Hesselberth, Jay, Gershon, Timothy, Wechsler-Reya, Robert, Foreman, Nicholas, Vibhakar, Rajeev
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Medulloblastoma (Research)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715400/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.555
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados