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MBRS-02. BET BROMODOMAIN PROTEIN-KINASE INHIBITOR COMBINATIONS FOR THE TREATMENT OF MEDULLOBLASTOMA

Recent sequencing studies have implicated many epigenetic regulators in medulloblastoma. The epigenetic reader protein Brd4 has been implicated in various cancers including medulloblastoma. Brd4 controls expression of the medulloblastoma essential genes MYC in G3 medulloblastomas, which have poor pr...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Ayad, Nagi, Suter, Robert, Robbins, David, Roussel, Martine
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715348/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.523
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