EPEN-22. SINGLE-CELL RNA SEQUENCING IDENTIFIES UPREGULATION OF IKZF1 IN PFA2 MYELOID SUBPOPULATION DRIVING AN ANTI-TUMOR PHENOTYPE

We have previously shown immune gene phenotype variations between posterior fossa ependymoma subgroups. PFA1 tumors chronically secrete IL-6, which pushes the infiltrating myeloid cells to an immune suppressive function. In contrast, PFA2 tumors have a more immune activated phenotype and have a bett...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Griesinger, Andrea, Prince, Eric, Donson, Andrew, Riemondy, Kent, Ritzman, Timothy, Harris, Faith, Amani, Vladimir, Handler, Michael, Hankinson, Todd, Grundy, Richard, Jackson, Andrew, Foreman, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Ependymoma
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715268/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.159
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados