DDEL-05. BLOOD-BRAIN BARRIER DISRUPTION AND ENHANCED RADIOSENSITIZERS EXTRAVASATION UPON FOCUSED ULTRASOUND FOR TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA

Poor prognosis of diffuse midline glioma, including diffuse intrinsic pontine glioma (DIPG), reflects the low efficacy of current treatment strategies, mainly due to (1) a largely intact blood-brain barrier (BBB) and (2) the proficiency of tumour tissues to upregulate multiple DNA repair genes, resu...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Hart, Elvin ‘t, Derieppe, Marc, Bruin, Maaike, Besse, Helena, Haumann, Rianne, Hoving, Eelco, Huitema, Alwin, Ries, Mario, van Vuurden, Dannis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Drug Delivery/Pharmacokinetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715181/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.040
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