DDEL-05. BLOOD-BRAIN BARRIER DISRUPTION AND ENHANCED RADIOSENSITIZERS EXTRAVASATION UPON FOCUSED ULTRASOUND FOR TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA

Poor prognosis of diffuse midline glioma, including diffuse intrinsic pontine glioma (DIPG), reflects the low efficacy of current treatment strategies, mainly due to (1) a largely intact blood-brain barrier (BBB) and (2) the proficiency of tumour tissues to upregulate multiple DNA repair genes, resu...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Hart, Elvin ‘t, Derieppe, Marc, Bruin, Maaike, Besse, Helena, Haumann, Rianne, Hoving, Eelco, Huitema, Alwin, Ries, Mario, van Vuurden, Dannis
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Drug Delivery/Pharmacokinetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715181/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.040
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