Imaged-guided focused ultrasound in combination with various formulations of doxorubicin for the treatment of diffuse intrinsic pontine glioma

Abstract Background Diffuse intrinsic pontine glioma (DIPG) is a notoriously difficult tumor to treat, with an overall survival of DIPG patients being only 11 months. One of the major obstacles for the effective treatment of DIPG is the blood–brain barrier (BBB). In order to circumvent the BBB, drug...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rianne Haumann, John I. Bianco, Piotr M. Waranecki, Pieter J. Gaillard, Gert Storm, Mario Ries, Dannis G. van Vuurden, Gertjan J. L. Kaspers, Esther Hulleman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2022-04-01
Cyfres:Translational Medicine Communications
Pynciau:
Diffuse intrinsic pontine glioma
Focused ultrasound
Blood–brain barrier
Liposomes
Nanomedicine
Doxorubicin
Mynediad Ar-lein:https://doi.org/10.1186/s41231-022-00115-7
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