DDEL-07. A PHASE I STUDY EXAMINING THE FEASIBILITY OF INTERMITTENT CONVECTION-ENHANCED DELIVERY (CED) OF MTX110 FOR THE TREATMENT OF CHILDREN WITH NEWLY DIAGNOSED DIFFUSE MIDLINE GLIOMAS

Convection-enhanced delivery (CED, the infusion of drugs under controlled pressure to the brain parenchyma via targeted micro-catheters, allows accurate anatomical targeting and delivery of higher (therapeutic) drug concentrations through clinically relevant volumes of brain tissue or tumor. Histone...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Zacharoulis, Stergios, Szalontay, Luca, Higgins, Dominic, Englander, Zachary, Jin, ZhenZhen, Garvin, James, Zylber, Rebecca, Stark, Eileen, Maddocks, Alexis, Sethi, Chankrit, Canoll, Peter, Dammnett, Steve, Cook, Craig, Feldstein, Neil, Bruce, Jeffrey
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Drug Delivery/Pharmacokinetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715104/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.042
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