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Wnt pathway modulation generates blastomere-derived mouse embryonic stem cells with different pluripotency features
PURPOSE: This study aimed to determine the role of Wnt pathway in mouse embryonic stem cell (mESC) derivation from single blastomeres isolated from eight-cell embryos and in the pluripotency features of the mESC established. METHODS: Wnt activator CHIR99021, Wnt inhibitor IWR-1-endo, and MEK inhibit...
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| Publicado no: | J Assist Reprod Genet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7714892/ https://ncbi.nlm.nih.gov/pubmed/33047186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-020-01964-7 |
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