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SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer

Metastatic breast cancer (MBC) is an extremely recalcitrant disease capable of bypassing current targeted therapies via engagement of several growth promoting pathways. SH2 containing protein tyrosine phosphatase-2 (SHP2) is an oncogenic phosphatase known to facilitate growth and survival signaling...

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書目詳細資料
發表在:Oncogene
Main Authors: Chen, Hao, Libring, Sarah, Ruddraraju, Kasi Viswanatharaju, Miao, Jinmin, Solorio, Luis, Zhang, Zhong-Yin, Wendt, Michael K.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714690/
https://ncbi.nlm.nih.gov/pubmed/33033382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01488-5
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