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SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer
Metastatic breast cancer (MBC) is an extremely recalcitrant disease capable of bypassing current targeted therapies via engagement of several growth promoting pathways. SH2 containing protein tyrosine phosphatase-2 (SHP2) is an oncogenic phosphatase known to facilitate growth and survival signaling...
Gespeichert in:
| Veröffentlicht in: | Oncogene |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7714690/ https://ncbi.nlm.nih.gov/pubmed/33033382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01488-5 |
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