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SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer
Metastatic breast cancer (MBC) is an extremely recalcitrant disease capable of bypassing current targeted therapies via engagement of several growth promoting pathways. SH2 containing protein tyrosine phosphatase-2 (SHP2) is an oncogenic phosphatase known to facilitate growth and survival signaling...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7714690/ https://ncbi.nlm.nih.gov/pubmed/33033382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01488-5 |
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