The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer

Drug resistance remains a barrier in the clinical treatment of ovarian cancer. Proteasomal and antioxidant activities play important roles in tumor drug resistance, and increasing evidence suggests the existence of an interaction between antioxidant and proteasomal activities. However, the mechanism...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Deng, Xinyue, Lin, Nan, Fu, Jiaying, Xu, Long, Luo, Haoge, Jin, Yao, Liu, Yanan, Sun, Liankun, Su, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714579/
https://ncbi.nlm.nih.gov/pubmed/33294122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4830418
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