p53 Affects PGC1α Stability Through AKT/GSK-3β to Enhance Cisplatin Sensitivity in Non-Small Cell Lung Cancer

Drug resistance greatly limits the therapeutic efficacy of treatment of non-small cell lung cancer (NSCLC). One of the important factors is the dysfunction of tumor suppressor p53. Recent studies have suggested that p53 suppresses tumors by regulating number of mitochondrial proteins, including pero...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Deng, Xinyue, Li, Yang, Gu, Shuang, Chen, Yingying, Yu, Bingbing, Su, Jing, Sun, Liankun, Liu, Yanan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471661/
https://ncbi.nlm.nih.gov/pubmed/32974127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01252
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