Humoral immune responses mediate the development of a restrictive phenotype of chronic lung allograft dysfunction

Understanding the distinct pathogenic mechanisms that culminate in allograft fibrosis and chronic graft failure is key in improving outcomes after solid organ transplantation. Here, we describe an F1 → parent orthotopic lung transplant model of restrictive allograft syndrome (RAS), a particularly fu...

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Detalhes bibliográficos
Publicado no:JCI Insight
Principais autores: Misumi, Keizo, Wheeler, David S., Aoki, Yoshiro, Combs, Michael P., Braeuer, Russell R., Higashikubo, Ryuji, Li, Wenjun, Kreisel, Daniel, Vittal, Ragini, Myers, Jeffrey, Lagstein, Amir, Walker, Natalie M., Farver, Carol F., Lama, Vibha N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714414/
https://ncbi.nlm.nih.gov/pubmed/33268593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136533
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