Local Origin of Mesenchymal Cells in a Murine Orthotopic Lung Transplantation Model of Bronchiolitis Obliterans

Bronchiolitis obliterans is the leading cause of chronic graft failure and long-term mortality in lung transplant recipients. Here, we used a novel murine model to characterize allograft fibrogenesis within a whole-lung microenvironment. Unilateral left lung transplantation was performed in mice acr...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Mimura, Takeshi, Walker, Natalie, Aoki, Yoshiro, Manning, Casey M., Murdock, Benjamin J., Myers, Jeffery L., Lagstein, Amir, Osterholzer, John J., Lama, Vibha N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2015
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450312/
https://ncbi.nlm.nih.gov/pubmed/25848843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.03.002
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