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Carbon monoxide, generated by heme oxygenase‐1, mediates the enhanced permeability and retention effect in solid tumors

The enhanced permeability and retention (EPR) effect is a unique pathophysiological phenomenon of solid tumors that sees biocompatible macromolecules (>40 kDa) accumulate selectively in the tumor. Various factors have been implicated in this effect. Herein, we report that heme oxygenase‐1 (HO‐1;...

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Bibliografski detalji
Izdano u:Cancer Sci
Glavni autori: Fang, Jun, Qin, Haibo, Nakamura, Hideaki, Tsukigawa, Kenji, Shin, Takashi, Maeda, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2012
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713620/
https://ncbi.nlm.nih.gov/pubmed/22145952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2011.02178.x
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