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Targeting REV7 effectively reverses 5-FU and oxaliplatin resistance in colorectal cancer

BACKGROUND: Despite an enormous research effort, patients diagnosed with advanced colorectal cancer (CRC) still have low prognosis after surgical resection and chemotherapy. The major obstacle for CRC treatment is chemoresistance to front line anti-cancer drugs, such as 5-fluorouracil (5-FU) and oxa...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Sun, Xianjun, Hou, Wenhou, Liu, Xin, Chai, Jie, Guo, Hongliang, Yu, Jinming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713438/
https://ncbi.nlm.nih.gov/pubmed/33292253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01668-z
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