Oxaliplatin/5-FU without Leucovorin Chemotherapy in Metastatic Colorectal Cancer

PURPOSE: Fluorouracil (5-FU) and leucovorin combination therapy have shown synergistic or additive effect against advanced colorectal cancer, but the frequency of mucositis and diarrhea is increased. Most previous studies have used high dose leucovorin (300~500 mg/m(2)). However, some studies of oxa...

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Bibliographic Details
Main Authors: Shim, Byoung Yong, Lee, Kang Moon, Cho, Hyeon-Min, Kim, Hyun Jin, Cho, Hong Joo, Yang, Jinmo, Kim, Jun-Gi, Kim, Hoon-Kyo
Format: Artigo
Language:Inglês
Published: Korean Cancer Association 2005
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785915/
https://ncbi.nlm.nih.gov/pubmed/19956516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2005.37.4.212
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