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AMPK maintains TCA cycle through sequential phosphorylation of PDHA to promote tumor metastasis

Cancer represents the leading public health problem throughout the world. Globally, about one out of six deaths is related to cancer, which is largely due to the metastatic lesions. However, there are no effective strategies for targeting cancer metastasis. Identification of the key druggable target...

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Vydáno v:Cell Stress
Hlavní autoři: Cai, Zhen, Peng, Danni, Lin, Hui-Kuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Shared Science Publishers OG 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713264/
https://ncbi.nlm.nih.gov/pubmed/33336150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2020.12.238
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