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A novel mutation in the ACAN gene in a family with autosomal dominant short stature and intervertebral disc disease

Heterozygous mutations in the ACAN gene have been reported in individuals with short stature and advanced bone age, with or without early-onset osteoarthritis and/or osteochondritis dissecans. We report a family with a phenotypic constellation carrying a novel mutation in the ACAN gene. The proband...

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Detalhes bibliográficos
Publicado no:Hum Genome Var
Main Authors: Uchida, Noboru, Shibata, Hironori, Nishimura, Gen, Hasegawa, Tomonobu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712780/
https://ncbi.nlm.nih.gov/pubmed/33298914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41439-020-00132-8
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