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A novel mutation in the ACAN gene in a family with autosomal dominant short stature and intervertebral disc disease

Heterozygous mutations in the ACAN gene have been reported in individuals with short stature and advanced bone age, with or without early-onset osteoarthritis and/or osteochondritis dissecans. We report a family with a phenotypic constellation carrying a novel mutation in the ACAN gene. The proband...

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Bibliografski detalji
Izdano u:Hum Genome Var
Glavni autori: Uchida, Noboru, Shibata, Hironori, Nishimura, Gen, Hasegawa, Tomonobu
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712780/
https://ncbi.nlm.nih.gov/pubmed/33298914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41439-020-00132-8
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