Phase I and II Clinical Trial Comparing the LBSap, Leishmune(®), and Leish-Tec(®) Vaccines against Canine Visceral Leishmaniasis

In this study, we performed a phase I and II clinical trial in dogs to evaluate the toxicity and immunogenicity of LBSap-vaccine prototype, in comparison to Leishmune(®) and Leish-Tec(®) vaccines. Twenty-eight dogs were classified in four groups: (i) control group received 1 mL of sterile 0.9% salin...

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Publicat a:Vaccines (Basel)
Autors principals: Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Mathias, Fernando Augusto Siqueira, Reis, Levi Eduardo Soares, Cardoso, Jamille Mirelle de Oliveira, de Brito, Rory Cristiane Fortes, Ker, Henrique Gama, Corrêa-Oliveira, Rodrigo, Giunchetti, Rodolfo Cordeiro, Reis, Alexandre Barbosa
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712644/
https://ncbi.nlm.nih.gov/pubmed/33212786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040690
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