A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden

Herein, we evaluated the treatment strategy employing a therapeutic heterologous vaccine composed of antigens of Leishmania braziliensis associated with MPL adjuvant (LBMPL vaccine) for visceral leishmaniasis (VL) in symptomatic dogs naturally infected by Leishmania infantum. Sixteen dogs received i...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Reis, Levi Eduardo Soares, Cardoso, Jamille Mirelle de Oliveira, Mathias, Fernando Augusto Siqueira, de Brito, Rory Cristiane Fortes, da Silva, Sydnei Magno, Gontijo, Nelder De Figueiredo, Ferreira, Sidney de Almeida, Valenzuela, Jesus G., Corrêa-Oliveira, Rodrigo, Giunchetti, Rodolfo Cordeiro, Reis, Alexandre Barbosa
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338076/
https://ncbi.nlm.nih.gov/pubmed/28321217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00217
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