A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden

Herein, we evaluated the treatment strategy employing a therapeutic heterologous vaccine composed of antigens of Leishmania braziliensis associated with MPL adjuvant (LBMPL vaccine) for visceral leishmaniasis (VL) in symptomatic dogs naturally infected by Leishmania infantum. Sixteen dogs received i...

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Publicado en:Front Immunol
Autores principales: Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Reis, Levi Eduardo Soares, Cardoso, Jamille Mirelle de Oliveira, Mathias, Fernando Augusto Siqueira, de Brito, Rory Cristiane Fortes, da Silva, Sydnei Magno, Gontijo, Nelder De Figueiredo, Ferreira, Sidney de Almeida, Valenzuela, Jesus G., Corrêa-Oliveira, Rodrigo, Giunchetti, Rodolfo Cordeiro, Reis, Alexandre Barbosa
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338076/
https://ncbi.nlm.nih.gov/pubmed/28321217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00217
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