LBSapSal-vaccinated dogs exhibit increased circulating T-lymphocyte subsets (CD4(+) and CD8(+)) as well as a reduction of parasitism after challenge with Leishmania infantum plus salivary gland of Lutzomyia longipalpis

BACKGROUND: The development of a protective vaccine against canine visceral leishmaniasis (CVL) is an alternative approach for interrupting the domestic cycle of Leishmania infantum. Given the importance of sand fly salivary proteins as potent immunogens obligatorily co-deposited during transmission...

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Detalhes bibliográficos
Main Authors: Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Ker, Henrique Gama, Moreira, Nádia das Dores, Mathias, Fernando Augusto Siqueira, Cardoso, Jamille Mirelle de Oliveira, Gontijo, Nelder Figueiredo, Bruna-Romero, Oscar, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Corrêa-Oliveira, Rodrigo, Giunchetti, Rodolfo Cordeiro, Reis, Alexandre Barbosa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943450/
https://ncbi.nlm.nih.gov/pubmed/24507702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-7-61
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